Chamber, a U.S.-based cardiology-focused healthcare technology company, has raised $60 million in Series A funding to expand its value-based care platform designed to support cardiologists and health plans in managing cardiovascular disease more effectively at scale.

The financing round was led by Frist Cressey Ventures, a healthcare investment firm focused on improving care delivery models, particularly in complex clinical areas such as chronic disease management. The round also included participation from General Catalyst, AlleyCorp, American Family Ventures, Company Ventures, Optum Ventures, Healthworx Ventures, and Black Opal Ventures. Additional capital included debt financing from HSBC Innovation Banking, reflecting a blended funding structure typical of late-stage healthcare infrastructure companies.

Founded to address the inefficiencies of traditional fee-for-service cardiology care, Chamber builds a workflow-integrated technology platform that uses data analytics and artificial intelligence to help clinicians identify high-risk patients, close care gaps, and reduce avoidable hospitalizations. The platform is embedded directly into cardiologists’ existing clinical workflows, allowing providers to act on patient insights without adding administrative burden.

The company’s Series A comes at a time when cardiovascular disease remains the leading driver of mortality and healthcare spending in the United States. Chamber positions itself as an infrastructure layer for “value-based cardiology,” a care model that rewards providers for patient outcomes rather than service volume. By aligning incentives between cardiologists and payers, the company aims to improve long-term outcomes while reducing system-wide costs.

According to the company, the newly raised capital will be used to accelerate expansion into additional U.S. markets, scale its clinical operations team, and invest further in its AI-powered care coordination tools. Chamber also plans to deepen partnerships with health plans and cardiology practices, building a broader network of providers participating in value-based arrangements.

The company currently works with a network of more than 500 cardiologists across multiple states and is continuing to expand its footprint as demand grows for alternative reimbursement models in specialty care. Its platform is designed not only for large health systems but also for independent cardiology practices seeking tools to compete in increasingly complex payer environments.

Chamber’s investors represent a mix of healthcare-focused venture capital firms and strategic backers with deep experience in insurance, provider networks, and healthcare infrastructure. Their participation signals continued confidence in the shift toward data-driven, outcomes-based care models in high-cost specialties such as cardiology.

With this latest financing, Chamber is positioning itself as a core infrastructure provider in the evolving cardiovascular care ecosystem, where technology-enabled coordination and risk management are becoming central to both clinical success and financial sustainability.

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